有机合成化学，荧光功能分子探针与生物诊疗传感
个人简介
杨征博士，讲师，现任化学系副主任。博士毕业于西北大学，导师李剑利教授和张生勇院士。研究方向为有机合成化学、光功能分子探针与生物诊疗传感。主持陕西省自然科技基础研究计划项目、陕西省科技厅专项科研项目、西安科技大学优秀青年基金、中国科学院分离分析化学开放基金项目等科研项目5项，西安科技大学教改项目2项，在Org.Lett.，J.Org.Chem.，Sens.ActuatorsB:Chem.，Anal.Chim.Acta、J.Mater.Chem.B等权威学术期刊发表SCI研究论文35篇，核心期刊论文6篇，引用次数超过500余次，两篇论文曾进入ESI行列，申请国家发明专利6项。获陕西高等学校科学技术奖特等奖、西安科技大学青年教师讲课比赛三等奖、西安科技大学优秀班主任、化学与化工学院教师讲课技能提升大赛一等奖。指导学生获“挑战杯”大学生课外学术科技作品竞赛省级二等奖、校级特等奖、陕西省化学实验邀请赛三等奖、陕西省高校化学视频大赛三等奖等。
科研项目
1.纳米功能化氮杂环金属配位调控NO荧光探针构建及环境生物应用，No.2018JQ2061。
2.碳纳米改性氮杂环配合物功能化NO荧光探针及其应用，No.2018YQ3-14。
3.乙二胺桥连氮杂环功能化Fe3+探针的构建及机理和应用研究，No.17JK0493。
4.耐酸性罗丹明螺酰胺用于超分辨荧光生物成像，No.KL–1702。
代表作
1.JiaoZhang,ShunshengZhao,ZhengYang,ZaiwenYang,ShuilanYang,XiangrongLiu.Hydrothermalsynthesisofblue-greenemittingcarbondotsbasedontheliquidproductsofbiodegradationofcoal.InternationalJournalofEnergyResearch.2021,45,9396–9407.
2.ZhengYang,HuiLi,TianTianXu,XiangrongLiu,ShunshengZhao,ZaiwenYang.AzaaromaticfunctionalizedrhodaminebasedfluorescentprobesforselectivedualchanneldetectionofClO-andCu2+inwatersamplesandlivingcells.ChemistryLetters.2020,49(11),1278–1281.
3.SiyueMa,JiabaoQiang,LinyangLi,YanMo,MengyaoShe,ZhengYang,PingLiu,ShengyongZhang,JianliLi.AnefficientbiosensorformonitoringAlzheimer’sdiseaseriskfactors:modulationanddisaggregationofAβaggregationprocess.JournalofMaterialsChemistryB.2019,7,4124-4132.
4.ZhengYang,MengyaoShe,SiyueMa,BingYin,PingLiu,XiangrongLiu,ShunshengZhao,JianliLi.Rhodaminebasedguanidinobenzimidazolefunctionalizedfluorescentprobefortetravalenttinanditsapplicationinlivingcellsimaging，SensorsandActuatorsB:Chemical,2017,242,872-879.
5.ZhengYang,YuanlongHe,XiangrongLiu,ShunshengZhao,ZaiwenYang,ShuilanYang.HighlyefficientapproachforhypochlorousacidsensinginwatersamplesandlivingcellsbasedonacylhydrazoneSchiffbasefunctionalizedfluorescentprobes.NewJournalofChemistry.2017,41,12250–12258.
6.ZhengYang,XinxinBai,SiyueMa,XiangrongLiu,ShunshengZhao,ZaiwenYang.AbenzoxazolefunctionalizedfluorescentprobeforselectiveFe3+detectionandintracellularimaginginlivingcells,AnalyticalMethods,2017,9,18-22.
7.MengyaoShe,ShaopingWu,ZhaohuiWang,SiyueMa,ZhengYang,BingYin,PingLiu,ShengyongZhang,JianliLi.ExplorationofcongenericHg(II)-mediatedchemosensorsdrivenbyS-Hgaffinity,andtheirapplicationinlivingsystem.SensorsandActuatorsB:Chemical.2017,247,128-138.
8.SiyueMa,YaqiWang,MengyaoShe,ShenWang,ZhengYang,PingLiu,ShengyongZhang.JianliLi.Designstrategiesandprogressonxanthenebasedfluorescentprobeformetalions.ReviewinAnalyticalChemistry.2017,36,20160024.
9.MengyaoShe,ZhengYang,LikaiHao,ZhaohuiWang,TianyouLuo,MartinObst,PingLiu,YehuaShen,ShengyongZhang,JianliLi.Anovelapproachtostudythestructure-propertyrelationshipsandapplicationsinlivingsystemsofmodularCu2+fluorescentprobes.ScientificReports.2016,6,28972.
10.ZhengYang,MengyaoShe,BingYin,LikaiHao,MartinObst,PingLiu,JianliLi*.Solvent-dependentTurn-onProbeforDualMonitoringofAg+andZn2+inLivingBiologicalSamples.AnalyticaChimicaActa.2015,868,53-59.
11.SiyueMa,ZhengYang,MengyaoShe,WeiSun,BingYin,PingLiu,ShengyongZhang,JianliLi.DesignandsynthesisoffunctionalizedrhodaminebasedprobesforspecificintracellularfluorescenceimagingofFe3+.DyesandPigments.2015,115,120-126.
12.ZhengYang,MengjiaWang,MengyaoShe,YangyangHuang,BingYin,PingLiu,JianliLi,ShengyongZhang.Newaliphaticandaromaticdialdehydebridgedturn-onprobesforhypochloritedetectioninbiologicalsamplesbasedonbis(fluorescein).SensorsandActuatorsB:Chemical.2014,202,656–662.
13.ZhengYang,LikaiHao,BingYin,MengyaoShe,MartinObst,AndreasKappler,JianliLi.Six-memberedspirocycletriggeredprobeforvisualizingHg2+inlivingcellsandbacteria-EPS-mineralaggregates.OrganicLetters.2013,15(17),4334-4337.
14.ZhengYang,MengyaoShe,JinZhang,XiaoxiangChen,YangyangHuang,HengyanZhu,PingLiu,JianliLi,ZhenShi.HighlysensitiveandselectiverhodamineSchiffbase“off-on”chemosensorsforCu2+imaginginlivingcells.SensorsandActuatorsB:Chemical.2013,176,482-487.
15.ZhengYang,MengyaoShe,BingYin,JihongCui,YuzeZhang,WeiSun,JianliLi,ZhenShi.Threerhodamine-based“offon”chemosensorswithhighselectivityandsensitivityforFe3+imaginginlivingcells.TheJournalofOrganicChemistry.2012,77,11431147.